The Nucleic Acid Company

Welcome to BioSpring®

At BioSpring, we are passionate about moving the elements of life. As a global leader in nucleic acid manufacturing and analysis, we are your trusted CDMO partner - delivering cutting-edge nucleic acid solutions, across all clinical phases and stages of drug development, into the commercial market. With almost three decades of experience, we have established ourselves as the premier partner for pharmaceutical and biotech companies, and academic institutions worldwide.

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Three decades of expertise

Industry leader in nucleic acid manufacturing and analysis since 1997​

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From research to commercial Production

Global supplier of commercial oligonucleotides, supporting 8 commercial programs

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Trusted by pharma & biotech worldwide

APIs manufactured for hundreds of clinical trials worldwide

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One source for manufacturing & analytical solutions

Support at every stage, creating a long-lasting partnership

About BioSpring

Pioneering Nucleic Acid Solutions

At the heart of modern therapeutics lies the promise of nucleic acids – the building blocks of life. These molecules, such as DNA and RNA, play a vital role in groundbreaking therapies, including treatments for genetic disorders, cancer, and infectious diseases. BioSpring has mastered the art and science of nucleic acid manufacturing and analysis, providing the highest quality nucleic acids like antisense oligonucleotides (ASOs), guide RNA (gRNA), messenger RNA (mRNA), and small interfering RNA (siRNA).

With our state-of-the-art facilities and a team of nucleic acid and analytical chemists, process engineers, and quality experts, we collaborate closely with our clients to provide innovative solutions. Our commitment to quality, innovation, and scalability drives the success of our clients’ therapeutic programs, no matter the complexity.

What are nucleic acid therapeutics?

Nucleic acid therapeutics represent a groundbreaking advancement in medicine. Unlike traditional drugs that target proteins, these therapies use strands of DNA or RNA to modify, silence, or repair disease-causing genes. This approach opens up possibilities for treating conditions that were previously considered untreatable.

Discover more about the diverse applications of nucleic acids here.

Manufacturing & Analytical solutions

BioSpring's Comprehensive Services

Your drug development journey deserves seamless support – no matter which phase you are in or how complex your molecule is. BioSpring delivers end-to-end solutions for nucleic acid manufacturing and analytics, tailored to your needs.

Powering Therapeutic Breakthroughs

Why Choose BioSpring?

Unparalleled Quality

With almost three decades in the industry and GMP certification since 2007, we have perfected our manufacturing processes to deliver high-quality nucleic acids at all scales, from early discovery through to commercial supply. Our outstanding track record in quality is supported by our highly experienced quality teams in both Quality Control (QC) and Quality Assurance (QA), ensuring the highest standards.

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Powering Therapeutic Breakthroughs

Why Choose BioSpring?

Client-Centric Services

Strategic project support is fundamental to every project’s success. That is why we provide a dedicated team of technical experts and a project manager, ensuring unmatched expertise and personalized guidance at every stage. This tailored approach allows us to fully support our clients’ therapeutic nucleic acid programs and unleash the full potential of their technologies.

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Powering Therapeutic Breakthroughs

Why Choose BioSpring?

Advanced Solutions

As market leader in nucleic acid manufacturing and analysis, we drive innovation through advanced analytical solutions, evaluation and implementation of new alternative manufacturing approaches, and cutting-edge purification technologies. Our commitment to continuous improvement ensures that we deliver cutting-edge solutions to enhance therapeutic efficacy and tolerability.

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Powering Therapeutic Breakthroughs

Why Choose BioSpring?

Full Regulatory Support

Navigating the complex regulatory landscape can be challenging, and our team is here to help. We offer comprehensive regulatory services, including documentation support for regulatory submissions (e.g., IND, NDA, BLA, DMF).

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Powering Therapeutic Breakthroughs

Why Choose BioSpring?

Scalability

Whether our clients need micrograms for preclinical development or kilograms for commercial production, our manufacturing processes are fully scalable, allowing to grow without the need to change suppliers.

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Advancing Your Nucleic Acid Therapeutics

As nucleic acid-based therapies continue to reshape modern medicine, BioSpring remains at the forefront of this transformative field. Our mission is to support the development of life-changing therapies, which improve patient outcomes. From personalized medicine to the treatment of widespread diseases that have been difficult or even impossible to treat until now, nucleic acids are driving the future of healthcare – and BioSpring is here to accelerate that progress.

We are more than just a CDMO – we are a partner invested in your success. Whether you are at the discovery phase or preparing for commercial launch, our team of experts will work with you to ensure that your nucleic acid therapy is ready for the next stage of development.

Let us move the elements of life together.